Sometimes, especially at long blitz/rapid but they usually lose. I am master level player (FM) and it took me almost 300 games of slow blitz to beat it with N odds and about 150 games to beat it with rook odds. I was beating it at Q odds (meaning more than 50%) but I suspect it might be even better now than it used to be.

Random data point: I'm rather weak (~1500 chess com) and I can take ~1/10 games off Queen odds starting with white (15+10) if i focus. It has some exploitable patterns still, I feel.

they can win with any odds. But, they can only barely win even with queen odds: https://lqo.leumon.com/

That's a bit misleading. I'm pretty sure grandmasters can win almost all games with queen odds at classical time controls